Scientists Find Leukemia-Linked Genes

According to research published in an issue of thethey may have the disease.
New Scientist, there may be eight genes that will
determine if an individual develops leukemia. The* 
 fatigue, tiredness, lack of energy
study was completed at Washington University in St.* 
 shortness of breath, difficulty breathing during
Louis by a team of researchers who usedphysical activity
"developed sequencing methods to look at the entire* 
 pale skin
genome of cells from an acute myelogenous* pinhead-sized red spots that appear just under the
leukemia (AML) tumor and from the patient's skin,skin
which helped narrow down and identify 10 varying* 
 joint and bone aches, pains
genes between the tissues."* 
 low white cell counts


* 
 black and blue marks or bruises that appear
The researchers were then able to pinpoint twowith no cause or reason
previously identifiable cancer-causing genes and* 
 fever or night sweats
eliminate them from the study. Then, the researchersSmoking Cessation Drugs
identified three of the genes out of the eight andWhile there are an array of factors involved in the
found them as having been tumor-suppressors.development of leukemia, smoking is one of the top
Tumor-suppressors genes cause cells that have beencauses that can be prevented if smoking cessation
damaged to die off, which is also known as apoptosisoccurs among the types of leukemia. There are an
or senescence, and because of this, cell populationsarray of smoking cessation drugs available in the
cannot replenish, thus causing weakness of the bodyUnited States for the 43.4 million American adults that
and the development of cancers such as leukemia.were reportedly smokers in 2007, according to the
The research is considered breakthrough and mayCenters for Disease Control and Prevention (CDC).
lead to the development of more treatments as well


as better-equipped screening processes and highlightThe CDC has issued the following list of cancers and
potential candidate�s who may be at a higher riskconditions as linked to individuals who smoke:
of developing the cancer.* 
 stomach
What Is Leukemia?* 
 pancreas
Leukemia is described as a �malignant disease of* 
 kidney
the bone marrow and blood,� according to the* 
 cervix
Leukemia and Lymphoma Society, which also* lung
describes the cancer as divided into four various* 
 bladder
categories including the following.

A plethora of smoking-cessation aids and
drugs currently exist to assist smokers in quitting, but
* 
 Acute Myelogenous Leukemia (AML)when some of these drugs also offer unintended and
* 
 Acute Lymphocytic Leukemia (ALL)severe side effects, it becomes important for
* 
 Chronic Myelogenous Leukemia (CML)individuals to know what they are consuming,
* 
 Chronic Lymphocytic Leukemia (CLL)whether a drug is prescribed by a physician or
Leukemia Causes, Signs and Symptomsavailable over-the-counter at the local grocery store.
According to the Leukemia and Lymphoma Society all


four varieties of the disease begin within a cell in theFor example, one such drug is known as Chantix or
bone marrow, which �undergoes a leukemicChampix (varenicline tartrate) and is a prescription
change and multiplies into many cells.� Each typemedication available to deter smoking addictions.
of leukemia is characterized by �the rate at whichHowever, the drug, from Pfizer, was recently linked
leukemia progresses and how the cells replace theto deadly side effects including suicidal thoughts,
normal blood and marrow cells.� However, theresuicidal tendencies, depression, behavioral changes
are common types of risk factors that areand moodiness.
associated with leukemia including the following:


* 
 tobacco smokeWhile the U.S. Food and Drug Administration (FDA)
* 
 radiation therapy when used during otherhave looked into the Chantix risks but have deemed
cancer treatmentsthe smoking cessation aid safe enough to remain on
* 
 chronic benzene exposurethe market for the time being. Chantix patients who
* 
 genetic diseases including down syndromehave been negatively impacted by the drug are
* 
 chemotherapy treatments and exposures toencouraged to speak with a pharmaceutical attorney
high doses of radiation therapyfor a free legal consultation on the potential for
Diagnosing leukemia can be difficult at times becauseparticipating in a Chantix class action lawsuit that may
of the similarities of leukemia signs and symptoms tooffer a return of monetary compensation to assist a
other types of conditions and illnesses, but, thevictim with psychiatric or additional medical bills or
Leukemia and Lymphoma Society described theconditions caused by the prescription cessation drug
following symptoms to watch for if a patient feelsChantix.