| Caffey disease also known infantile cortical | | | | body. Affected bones have included the mandible, tibia, |
| hyperostosis. The main feature of the disease is a | | | | ulna, clavicle, scapula, ribs, humerus, femur, fibula, skull, |
| peculiar cortical thickening of certain bones like the | | | | ilium, and metatarsals. Caffey disease has a worldwide |
| mandible, the clavicles, and the shafts of long bones. It | | | | distribution. Both sporadic and familial occurrences are |
| usually occurs during the first 6 months of life and | | | | reported. Caffey disease affects boys and girls |
| presents with periosteal new bone formation. The | | | | equally. |
| mandible is the most frequently affected bone, and its | | | | The disease has been reported to influence 3 per 1000 |
| involvement is virtually pathognomonic. In addition to | | | | infants younger than 6 months in the United States. |
| these changes, which can appear quite prominently on | | | | The familial form is inherited in an autosomal dominant |
| x-ray, the involved bones may also appear inflamed, | | | | fashion with variable penetrance. The familial form |
| with painful swelling and systemic fever often | | | | tends to have an earlier onset and is present at birth in |
| accompanying the illness. | | | | 24% of cases, with an average age at onset of 6.8 |
| It can simulate a systemic infection with fever and | | | | weeks. Infantile cortical hyperostosis is a self-limited |
| leucocytosis and is characterised by soft tissue | | | | condition, meaning that the disease resolves on its own |
| swellings over the clavicle. There are many symptoms | | | | without treatment, usually within 6-9 months. Long-term |
| of caffey disease some include soft-tissue swelling, | | | | deformities of the involved bones, including bony |
| bone lesions, and irritability. The swelling occurs | | | | fusions and limb-length inequalities. |
| suddenly, is deep, firm, and may be tender. Lesions are | | | | Get information on hairstyles, hair trends and hair care, |
| often asymmetric and may affect several parts of the | | | | including sections dealing with medium length hairstyles. |