| Caffey disease also known infantile cortical | | | | included the mandible, tibia, ulna, clavicle, scapula, ribs, |
| hyperostosis. The main feature of the disease is a | | | | humerus, femur, fibula, skull, ilium, and metatarsals. |
| peculiar cortical thickening of certain bones like the | | | | Caffey disease has a worldwide distribution. Both |
| mandible, the clavicles, and the shafts of long bones. | | | | sporadic and familial occurrences are reported. Caffey |
| It usually occurs during the first 6 months of life and | | | | disease affects boys and girls equally. |
| presents with periosteal new bone formation. The | | | | The disease has been reported to influence 3 per |
| mandible is the most frequently affected bone, and | | | | 1000 infants younger than 6 months in the United |
| its involvement is virtually pathognomonic. In addition | | | | States. The familial form is inherited in an autosomal |
| to these changes, which can appear quite prominently | | | | dominant fashion with variable penetrance. The familial |
| on x-ray, the involved bones may also appear | | | | form tends to have an earlier onset and is present at |
| inflamed, with painful swelling and systemic fever | | | | birth in 24% of cases, with an average age at onset |
| often accompanying the illness. | | | | of 6.8 weeks. Infantile cortical hyperostosis is a |
| It can simulate a systemic infection with fever and | | | | self-limited condition, meaning that the disease |
| leucocytosis and is characterised by soft tissue | | | | resolves on its own without treatment, usually within |
| swellings over the clavicle. There are many | | | | 6-9 months. Long-term deformities of the involved |
| symptoms of caffey disease some include soft-tissue | | | | bones, including bony fusions and limb-length |
| swelling, bone lesions, and irritability. The swelling | | | | inequalities. |
| occurs suddenly, is deep, firm, and may be tender. | | | | Get information on hairstyles, hair trends and hair |
| Lesions are often asymmetric and may affect | | | | care, including sections dealing with medium length |
| several parts of the body. Affected bones have | | | | hairstyles. |