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Stem Cells

Stem cells are primal cells common to all culture conditions can alter the behavior
multi-cellular organisms that retain the of cells, making it unclear whether the
ability to renew themselves through cell cells will behave in a similar manner in
division and can differentiate into a vivo. Considerable debate exists whether
wide range of specialized cell types. some proposed adult cell populations are
Research in the human stem cell field truly stem cells.
grew out of findings by Canadian • Totipotent stem cells are produced
scientists Ernest A. McCulloch and James from the fusion of an egg and sperm cell.
E. Till in the 1960s. Cells produced by the first few divisions
A stem cell is a primitive type of cell of the fertilized egg are also
that can be coaxed into developing into totipotent. These cells can differentiate
most of the 220 types of cells found in into embryonic and extraembryonic cell
the human body (e.g. blood cells, heart types.
cells, brain cells, etc). Some • Pluripotent stem cells are the
researchers regard them as offering the descendants of totipotent cells and can
greatest potential for the alleviation of differentiate into cells derived from the
human suffering since the development of three germ layers.
antibiotics. Over 100 million Americans • Multipotent stem cells can produce
and two billion other humans worldwide only cells of a closely related family of
suffer from diseases that may eventually cells.
be treated more effectively with stem • Unipotent cells can produce only one
cells or even cured. These include heart cell type, but have the property of
disease, diabetes, and certain types of self-renewal which distinguishes them
cancer. from non-stem cells.
Stem cells can be extracted from very Treatments
young human embryos -- typically from Medical researchers believe that stem
surplus frozen embryos left over from cell therapy has the potential to
in-vitro fertilization (IVF) procedures radically change the treatment of human
at fertility clinics. A couple undergoing disease. A number of adult stem cell
IVF is faced with four alternatives for therapies already exist, particularly
their 16 or so surplus embryos: bone marrow transplants that are used to
There are very few parents willing to treat leukaemia. In the future, medical
give their embryos to another couple for researchers anticipate being able to use
a variety of emotional reasons. There are technologies derived from stem cell
very few couples willing to receive them research to treat a wider variety of
for emotional reasons and because thawed diseases including cancer, parkinson's
embryos have such a low chance of disease, spinal cord injuries, and muscle
starting a pregnancy. Preservation can be damage, amongst a number of other
expensive. impairments and conditions. However,
Stem cell properties there still exists a great deal of social
These properties can be illustrated in and scientific uncertainty surrounding
vitro, using methods such as clonogenic stem cell research, which could possibly
assays, where the progeny of single cell be overcome through public debate and
is characterized. However, in vitro future research.




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