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Article #189: New Treatments For Prostate Cancer

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PROSTATE CANCER - NEW TREATMENT BY require a general anaesthetic (you would
RADIOTHERAPY not need to be put to sleep) making them
Research is continuing to try and improve lower risk. Both treatments also have
technology and techniques to allow fewer side effects than radical surgery
radiotherapy to the prostate gland to be ("prostatectomy"). However neither has
more effective and to have fewer side been in use long enough to know if it
effects. One way is to reduce the amount will prevent prostate cancer from coming
of radiation received by normal organs back as effectively as standard
(bladder, bowel etc) and this has been treatments (surgery and radiotherapy).
improving over the last few years with Cryotherapy is the killing of cancer
better machines and techniques such as cells by freezing them. Needles are
"conformal radiotherapy" and "IMRT". inserted into the prostate gland under
Work is also being carried out on local anaesthetic and liquid nitrogen is
combining brachytherapy with external passed along them to freeze the prostate
therapy to allow some of the benefits of and the cancer cells within it. Currently
brachytherapy (fewer side effects, higher it is being used for men whose prostate
overall dose to the prostate cancer) to cancer has come back despite a first more
be used for men with more advanced conventional treatment and so is only
prostate cancer without compromising the being trialled for use as a first
chance of cure. treatment option.
NEW HORMONE THERAPY FOR PROSTATE CANCER HIFU stands for high frequency
Some newer prostate cancer hormone ultrasound. Here ultrasound waves are
treatments have fewer side effects than directed to where there are cancer cells
older hormone based drugs. Some are also and are these are used to heat them up,
felt to be more effective. All the time thus killing them. In prostate cancer the
researchers are testing to try and find ultrasound probe would be put into the
the best hormone tablets or injections back passage and from here ultrasound
for use in prostate cancer. waves would be fired towards the prostate
Other research is going on to try and gland. The results so far have been good
work out the best time to give hormone in that the treatment is safe and
treatment in prostate cancer and whether effective.
it is best to combine this treatment with NEW TREATMENTS FOR PROSTATE CANCER IN
other types of treatments such as VERY EARLY STAGES OF DEVELOPMENT
chemotherapy or radiotherapy. Trials are There are a number of alternative
currently being run to answer these treatments which are still at a highly
questions and the results should be experimental stage of development. Gene
available in the next few years. therapy aims to replace the faulty genes
IMPROVEMENTS IN CHEMOTHERAPY TREATMENT in cancer cells with good ones which
FOR PROSTATE CANCER would allow the cell to self destruct if
In the past prostate cancer did not it felt it had become too mutated.
respond very well to chemotherapy drugs. (Cancer cells have lost this self
However now there are newer drugs which destruct ability and continue to grow and
are more powerful against prostate cancer divide despite having many abnormalities
and these have started to be used with which would normally force the cell to
more frequency in late prostate cancer die.) Vaccine treatment looks at ways of
which has already spread to other organs making the bodies own immune system
and which has become resistant to hormone recognise and kill cancerous sells.
treatments. The best drug found so far is Endothelin blockers are a new type of
Docetaxel, a new type of chemotherapy drug treatment which works by preventing
drug. It has several side effects the prostate cancer cells to grow.
including hair loss, nausea and risk of Many people may have heard that Vitamin D
infection. Doctors are now looking to see is being used in the treatment of
if Docetaxel would work even better as a prostate cancer however this therapy is
combination with other drugs. in the very early experimental stages and
USE OF BISPHOSPHONATE DRUGS FOR PROSTATE is no where near being used in clinics as
CANCER TREATMENT a cancer treatment. Vitamin D has been
These are a group of drugs which are most reported to block receptors on prostate
often used in treating osteoporosis. It cancer cells thereby slowing the rate of
has been recently found that they can their growth but there is NO clinical
also help reduce pain associated with evidence that this is in fact the case.
cancer deposits or secondaries in the Some researchers claim that the active
bones. They may also help reduce the risk form of Vitamin D slows the growth of
of these abnormal bones from breaking or prostate cancer but as yet this has only
fracturing, by slowing down the damage been tested on mice and other small
caused to the bone by the cancer. animals.
Research is ongoing to look at which of Beta-sitosterol is a herbal remedy that
these drugs is the best for treating people have started to associate with
prostate cancer with bone disease and prostate cancer treatment. This natural
when the best time to start treatment plant fat has apparently been proven
with these drugs is. effective for the treatment of an
ALTERNATIVE TO SURGERY FOR TREATMENT OF enlarged prostate but not necessarily
EARLY PROSTATE CANCER prostate cancer. According to research
There are 2 new treatments which are Beta-sitosterol MAY help to prevent the
being researched as an alternative to emergence of prostate cancer but this has
surgery for some men with localised not been clinically proven yet.
prostate cancer. Both options would not






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