| Most of the cases of this disease are | | | | causing some neurological problems, in bones |
| asymptomatic the disease is revealed as a | | | | causing pain and fractures, bone marrow |
| result of routine radiological examination of | | | | invasion causing cytopenias, liver metastases |
| the chest, but some patient also show | | | | resulting in biochemical imbalance, adrenal |
| symptoms and signs. The main symptoms include | | | | metastases is also common but it does not |
| cough, dyspnea, wheeze, stridor and sometimes | | | | results in insufficiency. systemic symptoms |
| pneumonia due to bronchial obstruction. | | | | like anorexia, cachexia, suppressed immunity, |
| | | | weight loss, fever are general symptoms |
| If the tumour grows within the lung tissue it | | | | practically found in all patients in the |
| can cause pain. Sometimes patient can | | | | later stages. |
| demonstrate symptoms of abscess formation due | | | | |
| to tumour caviation. The spreading of tumour | | | | In some patients we can find hypercalcemia |
| regionally can also result in dysphagia due | | | | and hypophosphatemia due to ectopic |
| to esophageal compression, hoarseness due to | | | | parathyroid hormone releasing tumours. |
| laryngeal nerve paralysis, dyspnea due to | | | | |
| phrenic nerve paralysis and horner syndrome | | | | Skeletal-connective tissue syndrome that is |
| due to sympathetic nerve paralysis. Pancoasts | | | | clubbing of fingers can also be seen in some |
| syndrome is result of extension of tumour in | | | | patients. Some times retinal blindness is |
| the apex of the lungs which involves last | | | | seen in patients suffering from small cell |
| cervical and first and second thoracic nerves | | | | cancer. |
| compression of the nerves results in shoulder | | | | |
| pain. | | | | Dermatological manifestations like |
| | | | dermatomyositis and acanthosis nigricans are |
| Cancer can spread in practically all organs. | | | | also seen in some patients but very rarely. |
| This type of cancer can spread in brain | | | | |