| Most of the cases of this disease are asymptomatic | | | | of cancer can spread in brain causing some |
| the disease is revealed as a result of routine | | | | neurological problems, in bones causing pain and |
| radiological examination of the chest, but some | | | | fractures, bone marrow invasion causing cytopenias, |
| patient also show symptoms and signs. The main | | | | liver metastases resulting in biochemical imbalance, |
| symptoms include cough, dyspnea, wheeze, stridor | | | | adrenal metastases is also common but it does not |
| and sometimes pneumonia due to bronchial | | | | results in insufficiency. systemic symptoms like |
| obstruction. | | | | anorexia, cachexia, suppressed immunity, weight loss, |
| If the tumour grows within the lung tissue it can | | | | fever are general symptoms practically found in all |
| cause pain. Sometimes patient can demonstrate | | | | patients in the later stages. |
| symptoms of abscess formation due to tumour | | | | In some patients we can find hypercalcemia and |
| caviation. The spreading of tumour regionally can also | | | | hypophosphatemia due to ectopic parathyroid |
| result in dysphagia due to esophageal compression, | | | | hormone releasing tumours. |
| hoarseness due to laryngeal nerve paralysis, dyspnea | | | | Skeletal-connective tissue syndrome that is clubbing |
| due to phrenic nerve paralysis and horner syndrome | | | | of fingers can also be seen in some patients. Some |
| due to sympathetic nerve paralysis. Pancoasts | | | | times retinal blindness is seen in patients suffering |
| syndrome is result of extension of tumour in the | | | | from small cell cancer. |
| apex of the lungs which involves last cervical and first | | | | Dermatological manifestations like dermatomyositis |
| and second thoracic nerves compression of the | | | | and acanthosis nigricans are also seen in some |
| nerves results in shoulder pain. | | | | patients but very rarely. |
| Cancer can spread in practically all organs. This type | | | | |