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Brca Breast Cancer Genes

Women who have BRCA breast cancer(central or eastern European) Jewish
genetic mutations are just as likely toheritage [one reason why the study was
survive as other women who get breastdone in Israel].
cancer, according to a new studyUsing the Israeli National Cancer
published in the New England Journal ofRegistry, the researchers were able to
Medicine.compare two large groups of BCRA
Women with BRCA1 and BRCA2 genes arecarriers and non-carriers with breast
more likely to get breast cancer. It wascancer. They tested the DNA from stored
also widely believed that those withtumor specimens from patients treated in
hereditary breast cancer from BRCA1Israel between 1987- 1998, and then
mutations had worse outcomes. This newreviewed the medical records from women
study, tracked two groups of women withwhose specimens were collected. The
breast cancer in Israel, one with themutation was found in about 10% of the
inherited BRCA1 and BRCA2 mutations, andwomen who were of Ashkenazi Jewish
the other without. The researchers foundheritage. The ten year survival rates
no significant difference in death ratesbetween women who had the mutation and
between the two groups. Between 5 and 10those who did not were similar.
percent of all breast cancers areThis news should prove reassuring for
hereditary and are more likely to occurwomen who carry the BRCA mutations and
with women from certain ethnicworry about breast cancer survival.
backgrounds like people of Ashkenazi



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