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Brca Breast Cancer Genes

Women who have BRCA breast cancer geneticJewish heritage [one reason why the study was
mutations are just as likely to survive asdone  in  Israel].
other women who get breast cancer, according
to a new study published in the New EnglandUsing the Israeli National Cancer Registry,
Journal  of  Medicine.the researchers were able to compare two
large groups of BCRA carriers and
Women with BRCA1 and BRCA2 genes are morenon-carriers with breast cancer. They tested
likely to get breast cancer. It was alsothe DNA from stored tumor specimens from
widely believed that those with hereditarypatients treated in Israel between 1987-
breast cancer from BRCA1 mutations had worse1998, and then reviewed the medical records
outcomes. This new study, tracked two groupsfrom women whose specimens were collected.
of women with breast cancer in Israel, oneThe mutation was found in about 10% of the
with the inherited BRCA1 and BRCA2 mutations,women who were of Ashkenazi Jewish heritage.
and the other without. The researchers foundThe ten year survival rates between women who
no significant difference in death rateshad the mutation and those who did not were
between the two groups. Between 5 and 10similar.
percent of all breast cancers are hereditary
and are more likely to occur with women fromThis news should prove reassuring for women
certain ethnic backgrounds like people ofwho carry the BRCA mutations and worry about
Ashkenazi (central or eastern European)breast cancer survival.



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