Brca Breast Cancer Genes

Women who have BRCA breast cancer geneticeastern European) Jewish heritage [one reason why
mutations are just as likely to survive as otherthe study was done in Israel].
women who get breast cancer, according to a newUsing the Israeli National Cancer Registry, the
study published in the New England Journal ofresearchers were able to compare two large groups
Medicine.of BCRA carriers and non-carriers with breast cancer.
Women with BRCA1 and BRCA2 genes are moreThey tested the DNA from stored tumor specimens
likely to get breast cancer. It was also widelyfrom patients treated in Israel between 1987- 1998,
believed that those with hereditary breast cancerand then reviewed the medical records from women
from BRCA1 mutations had worse outcomes. Thiswhose specimens were collected. The mutation was
new study, tracked two groups of women withfound in about 10% of the women who were of
breast cancer in Israel, one with the inherited BRCA1Ashkenazi Jewish heritage. The ten year survival
and BRCA2 mutations, and the other without. Therates between women who had the mutation and
researchers found no significant difference in deaththose who did not were similar.
rates between the two groups. Between 5 and 10This news should prove reassuring for women who
percent of all breast cancers are hereditary and arecarry the BRCA mutations and worry about breast
more likely to occur with women from certain ethniccancer survival.
backgrounds like people of Ashkenazi (central or